Most of the research that has been accomplished to date involves GSCI staff trained in modern research methods, working with Elders. The combination of expertise in modern methods and traditional knowledge results in research that showcases the best of both. Most of GSCI's research takes place on the land because Gwich'in traditional knowledge and language are rooted in the land.

Over 100 research projects have been carried out since 1993. Many of these projects were collaborative in nature and carried out over several years with funds raised from outside sources.  Our partners have included Gwich’in communities, local schools, universities, museums, governments, co-management boards, other First Nations, corporations, foundations and public organizations. Research has revolved around the study of place names and traditional land use, ethno-botany, ethno-archaeology, elder's biographies, genealogy, a Gwich'in language dictionary, the replication of 19th century caribou skin clothing, and the identification of National Historic Sites in the Gwich'in Settlement Region.

A number of GSCI research projects have also benefited from the involvement of graduate students from across Canada. Both parties benefit from the experience. The GSCI acquires expertise in a particular area, and the student is able to complete research/fieldwork for their degree. Masters and Ph.D students have come from the fields of linguistics, ethnobotany and anthropology (including the sub-disciplines of archaeology and cultural anthropology).